Description

Gpr4 Antagonist 1 CAS NO 1197879-16-5 is a potent and selective small molecule inhibitor of the G Protein-Coupled Receptor 4 (GPR4), a key target in inflammatory and oncological research. This high-purity compound is essential for advancing drug discovery programs and elucidating complex signaling pathways in cellular models. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on developing novel therapeutics for cancer, autoimmune diseases, and metabolic disorders.

Application

• Drug Discovery & Development: A critical tool for high-throughput screening (HTS) and lead optimization in programs targeting GPR4-mediated diseases.
• Biochemical & Cellular Assays: Used to study GPR4 receptor function, ligand binding, and downstream signaling cascades in vitro.
• Inflammation Research: Investigates the role of GPR4 in inflammatory responses, potentially for developing anti-inflammatory agents.
• Oncology Research: Explores the involvement of GPR4 in tumor microenvironment regulation, angiogenesis, and cancer cell proliferation.
• Metabolic Disorder Studies: Applied in research focused on metabolic pathways where GPR4 signaling is implicated.
• Academic & Contract Research: Serves as a reliable reference standard and pharmacological probe in basic and applied life science research.

Basic Information

Product Name	Gpr4 Antagonist 1
CAS No.	1197879-16-5
Molecular Formula	C₂₀H₂₀N₄O₃S
Molecular Weight	396.46 g/mol
Synonyms	GPR4 Antagonist 1; 2-(4-((2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)sulfonyl)piperazin-1-yl)-N-(3,4-dimethylphenyl)acetamide; GPR4 inhibitor; GPR4 antagonist; GPR4 blocker; GPR4 signaling inhibitor; 1197879-16-5; GPR4 Antagonist
EINECS	Contact for details

Quality Control

Our Gpr4 Antagonist 1 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity suitable for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment to guarantee traceability and compliance with your research standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C under inert atmosphere. The compound is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with reference structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.