Description

4-Fluoro-3-Pyrrolidinobenzaldehyde is a high-value fluorinated aromatic aldehyde building block, specifically engineered for advanced pharmaceutical and agrochemical synthesis. Its molecular structure, featuring a pyrrolidine substituent and a formyl group on a fluorinated benzene ring, makes it a critical intermediate for constructing complex molecules with enhanced biological activity and metabolic stability. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific fluorinated motifs into their target compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Research: Used in developing advanced herbicides, fungicides, and insecticides where the fluorine atom and pyrrolidine group can improve efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and organometallic chemistry.
• Material Science Precursor: Employed in the synthesis of organic electronic materials and liquid crystals, where its structure can influence charge transport and self-assembly properties.
• Chemical Biology Probes: Utilized to create fluorescent tags and molecular probes for studying biological processes and target engagement.

Basic Information

Product Name	4-Fluoro-3-Pyrrolidinobenzaldehyde
CAS No.	1197193-31-9
Molecular Formula	C11H12FNO
Molecular Weight	193.22 g/mol
Synonyms	3-(Pyrrolidin-1-yl)-4-fluorobenzaldehyde; 4-Fluoro-3-(1-pyrrolidinyl)benzaldehyde; 1-(4-Formyl-2-fluorophenyl)pyrrolidine; Benzaldehyde, 4-fluoro-3-(1-pyrrolidinyl)-; 4-Fluoro-3-pyrrolidin-1-ylbenzaldehyde
EINECS	Contact for details

Quality Control

Every batch of 4-Fluoro-3-Pyrrolidinobenzaldehyde is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality system is designed to support cGMP and ISO standards for advanced intermediates, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.