Description

2-Trifluoromethyl-6,7-dihydro-[1]pyrindin-5-one is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core structure, featuring a fused pyrindinone ring system substituted with a trifluoromethyl group, makes it a critical intermediate for developing novel bioactive molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of new active ingredients. Its unique properties facilitate the exploration of structure-activity relationships in medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in areas targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory therapies.
• Agrochemical Research: Serves as a building block for synthesizing novel herbicides, fungicides, and insecticides, leveraging the biological activity-enhancing properties of the trifluoromethyl group.
• Material Science Precursor: Used in the development of advanced organic materials, including organic light-emitting diodes (OLEDs) and liquid crystals, where fluorinated heterocycles improve stability and electronic properties.
• Chemical Biology Probe: Employed in academic and industrial research to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Trifluoromethyl-6,7-dihydro-[1]pyrindin-5-one
CAS No.	1196155-83-5
Molecular Formula	C10H8F3NO
Molecular Weight	215.17 g/mol
Synonyms	5-Oxo-2-(trifluoromethyl)-6,7-dihydro-1H-cyclopenta[b]pyridine; 2-(Trifluoromethyl)-6,7-dihydro-5H-cyclopenta[b]pyridin-5-one; 6,7-Dihydro-2-(trifluoromethyl)-5H-cyclopenta[b]pyridin-5-one; 2-Trifluoromethyl-5-oxo-6,7-dihydro-1H-cyclopenta[b]pyridine; 5H-Cyclopenta[b]pyridin-5-one, 6,7-dihydro-2-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-Trifluoromethyl-6,7-dihydro-[1]pyrindin-5-one is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. For advanced applications, we offer development and production under cGMP guidelines to support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.