Description

2-Chloro-5-Fluoropyridin-4-Ol is a high-purity fluorinated pyridine derivative, a crucial building block in advanced organic synthesis. This compound is valued for its unique halogenated structure, which enables precise molecular modifications in complex chemical processes. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific fluoropyridine motifs.

Basic Information

Product Name	2-Chloro-5-Fluoropyridin-4-Ol
CAS No.	1196153-96-4
Molecular Formula	C5H3ClFNO
Molecular Weight	147.54 g/mol
Synonyms	4-Hydroxy-2-chloro-5-fluoropyridine; 2-Chloro-5-fluoro-4-hydroxypyridine; 2-Chloro-5-fluoro-4-pyridinol; 5-Fluoro-2-chloropyridin-4-ol; 2-Chloro-5-fluoropyridin-4-ol; 4-Pyridinol, 2-chloro-5-fluoro-; 2-Chloro-5-fluoro-4(1H)-pyridinone (tautomer)
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Fluoropyridin-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.