Description

5-Amino-2-(Trifluoromethyl)Pyridin-4-Ol, 4-Hydroxy-6-(Trifluoromethyl)Pyridin-3-Amine is a high-value trifluoromethyl-substituted pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, combining amino and hydroxyl functionalities with the electron-withdrawing trifluoromethyl group, makes it indispensable for creating novel compounds with tailored properties. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science: Building block for creating specialty polymers, liquid crystals, and organic electronic materials that require specific fluorinated components.
• Chemical Synthesis: Versatile reagent for constructing complex heterocyclic compounds in medicinal and process chemistry.
• Fluorine Chemistry: Valuable scaffold for studying structure-activity relationships (SAR) in fluorinated compound libraries.

Basic Information

Product Name	5-Amino-2-(Trifluoromethyl)Pyridin-4-Ol, 4-Hydroxy-6-(Trifluoromethyl)Pyridin-3-Amine
CAS No.	1196153-82-8
Molecular Formula	C6H5F3N2O
Molecular Weight	178.11 g/mol
Synonyms	4-Hydroxy-6-(trifluoromethyl)pyridin-3-amine; 5-Amino-2-(trifluoromethyl)pyridin-4-ol; 3-Amino-4-hydroxy-6-(trifluoromethyl)pyridine; 4-Hydroxy-6-(trifluoromethyl)-3-pyridinamine; 5-Amino-4-hydroxy-2-(trifluoromethyl)pyridine; 1196153-82-8; 4-Hydroxy-6-trifluoromethylpyridin-3-ylamine
EINECS	Contact for details

Quality Control

Our production of 5-Amino-2-(Trifluoromethyl)Pyridin-4-Ol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All material is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong acids, strong bases, and oxidizing agents. For long-term storage, consider an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.