Description

2-(3-Bromophenyl)Ethanesulfonyl Chloride is a versatile and high-purity organic intermediate, specifically a sulfonyl chloride derivative, essential for introducing the sulfonamide functional group into target molecules. Its core value lies in enabling precise chemical synthesis, offering a reactive handle for constructing complex pharmacophores and advanced materials. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for drug discovery and the development of novel chemical entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing sulfonamide moieties with potential biological activity.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the sulfonamide group can enhance efficacy and selectivity.
• Material Science: Serves as a monomer or cross-linking agent in the creation of specialized polymers, resins, and advanced functional materials.
• Chemical Biology & Proteomics: Acts as a reactive probe or labeling agent for modifying proteins and studying biochemical pathways.
• Organic Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitution reactions to create complex, bromine-functionalized aromatic systems.
• Library Synthesis for Drug Discovery: A valuable reagent for generating diverse compound libraries in high-throughput screening campaigns to identify new drug leads.

Basic Information

Product Name	2-(3-Bromophenyl)Ethanesulfonyl Chloride
CAS No.	1196152-18-7
Molecular Formula	C8H8BrClO2S
Molecular Weight	283.57 g/mol
Synonyms	2-(3-Bromophenyl)ethanesulfonyl chloride; 1-Bromo-3-(2-chlorosulfonylethyl)benzene; 3-Bromophenethylsulfonyl chloride; (3-Bromophenyl)ethanesulfonyl chloride; 2-(3-Bromophenyl)ethane-1-sulfonyl chloride; 1196152-18-7; 3-Bromo-benzenesulfonyl chloride, ethane-; 2-(3-Bromophenyl)ethylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2-(3-Bromophenyl)Ethanesulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR, and IR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.