Description

2-(Pyrrolidin-3-Yl)-5-(Trifluoromethyl)Pyridine is a high-value, heterocyclic organic compound featuring a pyridine core substituted with a pyrrolidine ring and a trifluoromethyl group. This unique molecular architecture makes it a critical pharmaceutical intermediate and building block for medicinal chemistry research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Medicinal Chemistry Building Block: Used extensively in lead optimization and structure-activity relationship (SAR) studies due to its privileged scaffold.
• Agrochemical Research: Serves as a core structure for developing new active ingredients for crop protection products.
• Chemical Biology Probe Synthesis: Utilized in creating molecular tools for studying biological pathways and target validation.
• Ligand Development: Acts as a precursor for ligands used in catalysis and material science applications.

Basic Information

Product Name	2-(Pyrrolidin-3-Yl)-5-(Trifluoromethyl)Pyridine
CAS No.	1196146-55-0
Molecular Formula	C10H11F3N2
Molecular Weight	216.20 g/mol
Synonyms	5-(Trifluoromethyl)-2-(3-pyrrolidinyl)pyridine; 2-(3-Pyrrolidinyl)-5-(trifluoromethyl)pyridine; 3-[5-(Trifluoromethyl)pyridin-2-yl]pyrrolidine; 5-(Trifluoromethyl)-2-pyrrolidin-3-ylpyridine; 2-(Pyrrolidin-3-yl)-5-(trifluoromethyl)pyridine; 1196146-55-0
EINECS	Contact for details

Quality Control

Our 2-(Pyrrolidin-3-Yl)-5-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and chemical identity. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.