Description

(3-Chloro-5-Methoxyphenyl)Methanesulfonyl Chloride is a high-purity, versatile sulfonyl chloride derivative serving as a critical building block in advanced organic synthesis. Its value lies in its dual reactive sites, enabling its use as a key intermediate for constructing complex molecules with specific functionalities. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting sulfonamide-based therapeutics.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides that require the (3-chloro-5-methoxyphenyl) moiety.
• Functional Material Research: Serves as a monomer or cross-linking agent in the creation of specialty polymers, resins, and advanced materials with tailored properties.
• Chemical Biology & Proteomics: Employed as a reactive handle for bioconjugation, labeling biomolecules, or creating activity-based probes for enzyme studies.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing client-specific compounds.
• Academic & R&D Laboratories: Utilized in research institutions for methodological development and exploring new chemical reactions involving sulfonyl chloride chemistry.

Basic Information

Product Name	(3-Chloro-5-Methoxyphenyl)Methanesulfonyl Chloride
CAS No.	1194374-68-9
Molecular Formula	C8H8Cl2O3S
Molecular Weight	255.12 g/mol
Synonyms	3-Chloro-5-methoxybenzenemethanesulfonyl chloride; 1-Chloro-3-methoxy-5-(chloromethylsulfonyl)benzene; (3-Chloro-5-methoxyphenyl)methanesulfonyl chloride; Methanesulfonyl chloride, (3-chloro-5-methoxyphenyl)-; 3-Chloro-5-methoxybenzylsulfonyl chloride; (3-Cl-5-MeO-Ph)CH2SO2Cl
EINECS	Contact for details

Quality Control

Our (3-Chloro-5-Methoxyphenyl)Methanesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP (current Good Manufacturing Practice) compliance for pharmaceutical applications, and our quality protocols are designed to meet the stringent requirements of global regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.