Description

n-((2-Hydroxy-1-Hydroxymethyl)Ethyl)-9-Oxo-11.Alpha.,15S-Dihydroxy-17-Phenyl-18,19,20-Trinor-Prosta-5Z,13E-Dien-1-Amide is a high-purity synthetic prostaglandin derivative, a key advanced intermediate in pharmaceutical research and development. This compound is valued for its precise stereochemistry and functional groups, which are critical for modulating biological pathways in medicinal chemistry. It is primarily utilized by R&D scientists and process chemists in the pharmaceutical and biotechnology industries for the synthesis of novel therapeutic agents targeting inflammation, ocular conditions, and other prostaglandin-mediated processes.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel prostaglandin-based drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new compounds with optimized potency and selectivity.
• Ophthalmic Drug Development: Serves as a precursor in the research of prostaglandin analogues for treating glaucoma and ocular hypertension.
• Inflammation & Pain Research: Employed in preclinical research to investigate pathways related to inflammation, pain, and fever.
• Process Development & Scale-up: Used in optimizing synthetic routes and scaling up production for clinical trial material (CTM) and commercial manufacturing.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	n-((2-Hydroxy-1-Hydroxymethyl)Ethyl)-9-Oxo-11.Alpha.,15S-Dihydroxy-17-Phenyl-18,19,20-Trinor-Prosta-5Z,13E-Dien-1-Amide
CAS No.	1193782-16-9
Molecular Formula	C29H41NO6
Molecular Weight	499.65 g/mol
Synonyms	11α,15S-Dihydroxy-17-phenyl-18,19,20-trinor-prosta-5Z,13E-dien-9-one-1-carboxamide, N-[(2-Hydroxy-1-(hydroxymethyl)ethyl)]; Prostaglandin F2α phenyl trinor amide derivative; 17-Phenyl-18,19,20-trinor-PGF2α-1-ethanolamide; 9-Oxo-11α,15S-dihydroxy-17-phenyl-prosta-5Z,13E-dien-1-amide ethanol derivative; Phenyl-trinor prostaglandin amide intermediate; CAS 1193782-16-9
EINECS	Contact for details

Quality Control

Our n-((2-Hydroxy-1-Hydroxymethyl)Ethyl)-9-Oxo-11.Alpha.,15S-Dihydroxy-17-Phenyl-18,19,20-Trinor-Prosta-5Z,13E-Dien-1-Amide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.