Description

2-Bromo-6-(Trifluoromethyl)Pyridine-3-Carbaldehyde is a high-value, multi-functional pyridine derivative and a versatile chemical building block. Its molecular structure, featuring both a bromine substituent and a trifluoromethyl group, makes it a critical intermediate for constructing complex molecules in advanced research and development. This compound is primarily sought after by pharmaceutical, agrochemical, and material science industries for use in cross-coupling reactions, ligand synthesis, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the biological activity of the pyridine and trifluoromethyl motifs.
• Material Science & Ligand Chemistry: Serves as a building block for creating specialized ligands for catalysis and functional materials, including metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to form new carbon-carbon and carbon-nitrogen bonds.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic pathways and creating compound libraries for screening.

Basic Information

Product Name	2-Bromo-6-(Trifluoromethyl)Pyridine-3-Carbaldehyde
CAS No.	1192263-89-0
Molecular Formula	C7H3BrF3NO
Molecular Weight	253.99 g/mol
Synonyms	2-Bromo-6-(trifluoromethyl)nicotinaldehyde; 3-Formyl-2-bromo-6-(trifluoromethyl)pyridine; 2-Bromo-6-trifluoromethylpyridine-3-carboxaldehyde; 6-(Trifluoromethyl)-2-bromopyridine-3-carbaldehyde; 2-Bromo-6-(trifluoromethyl)-3-pyridinecarboxaldehyde; 3-Pyridinecarboxaldehyde, 2-bromo-6-(trifluoromethyl)-; 2-Bromo-6-(trifluoromethyl)-3-formylpyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-(Trifluoromethyl)Pyridine-3-Carbaldehyde is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.