Description

Benzofuran-7-Sulfonyl Chloride CAS NO 1191030-88-2 is a high-purity, reactive sulfonyl chloride derivative of benzofuran, serving as a critical building block in advanced organic synthesis. Its value lies in enabling the efficient introduction of the benzofuran-7-sulfonyl moiety, a key functional group for modulating the physicochemical properties of target molecules. This intermediate is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Research: Used in creating novel herbicides, fungicides, and insecticides by acting as a sulfonating agent for bioactive molecules.
• Material Science: Serves as a precursor for functional polymers and advanced materials where the benzofuran-sulfonamide structure imparts specific electronic or binding properties.
• Chemical Biology & Proteomics: Utilized as a reactive handle for labeling or modifying biomolecules to study protein function and interactions.
• Dye & Pigment Synthesis: Intermediate in the production of specialized dyes and optical materials.
• Cross-Coupling Reactions: Acts as an electrophile in palladium-catalyzed and other metal-mediated coupling reactions to form complex biaryl structures.

Basic Information

Product Name	Benzofuran-7-Sulfonyl Chloride
CAS No.	1191030-88-2
Molecular Formula	C8H5ClO3S
Molecular Weight	216.64 g/mol
Synonyms	7-Benzofuransulfonyl chloride; 1-Benzofuran-7-sulfonyl chloride; Benzofuran-7-sulfonyl chloride; 7-Sulfonylchloridobenzofuran; 2,3-Benzofuran-7-sulfonyl chloride; 7-Chlorosulfonylbenzofuran; Benzofuranyl-7-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our Benzofuran-7-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.