Description

Indol-4-Yl Sulfonyl Chloride is a specialized sulfonyl chloride derivative of indole, serving as a critical building block in advanced organic synthesis. Its primary value lies in its high reactivity as a sulfonylation reagent, enabling the efficient introduction of the indol-4-ylsulfonyl moiety into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in kinase inhibitor and other small molecule therapeutic research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific sulfonamide functionalities.
• Chemical Biology Probe Development: Employed to create activity-based probes for studying enzyme function and protein interactions.
• Material Science Research: A precursor for functionalized polymers and advanced organic materials with tailored properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke intermediates for client projects.

Basic Information

Product Name	Indol-4-Yl Sulfonyl Chloride
CAS No.	1191028-29-1
Molecular Formula	C8H6ClNO2S
Molecular Weight	215.66 g/mol
Synonyms	1H-Indole-4-sulfonyl chloride; 4-Indolesulfonyl chloride; Indole-4-sulfonyl chloride; 4-Sulfonylchloride indole; 1H-Indol-4-ylsulfonyl chloride; 1191028-29-1; SCHEMBL21806427
EINECS	Contact for details

Quality Control

Our Indol-4-Yl Sulfonyl Chloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.