Description

5,7-Difluorobenzothiazole is a high-value fluorinated heterocyclic building block, a key intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs). Its molecular structure, featuring a benzothiazole core with strategic fluorine substitutions, is engineered to impart enhanced metabolic stability, lipophilicity, and binding affinity in target molecules. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with optimized properties.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas, where the fluorobenzothiazole moiety is a privileged scaffold.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, leveraging fluorine's ability to improve biological activity and environmental stability.
• Material Science Research: Serves as a building block for organic electronic materials, including OLED (Organic Light-Emitting Diode) emitters and charge transport materials.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for catalysis and molecular recognition applications in fine chemical synthesis.
• Fluorescent Probe and Dye Chemistry: Acts as a core structure for developing sensitive fluorescent tags and dyes used in bio-imaging and diagnostic assays.

Basic Information

Product Name	5,7-Difluorobenzothiazole
CAS No.	1190322-04-3
Molecular Formula	C7H3F2NS
Molecular Weight	171.17 g/mol
Synonyms	5,7-Difluoro-1,3-benzothiazole; 5,7-Difluorobenzo[d]thiazole; Benzothiazole, 5,7-difluoro-; 2,4-Difluorobenzothiazole (common misnomer, verify structure); 5,7-Difluoro-benzo[d]thiazole
EINECS	Contact for details

Quality Control

Our 5,7-Difluorobenzothiazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.