Description

6-Fluoro-7-Azaindole-3-Carboxaldehyde is a high-value fluorinated heterocyclic building block of significant interest in modern synthetic chemistry. This compound matters as a versatile precursor for constructing complex molecular architectures, particularly in the development of novel pharmaceuticals and agrochemicals. It is primarily needed by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for lead optimization and the synthesis of targeted bioactive molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of kinase inhibitors, receptor antagonists, and other small-molecule drug candidates targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atom and azaindole core can enhance biological activity and environmental stability.
• Chemical Biology Probe: Serves as a building block for creating fluorescent tags, molecular probes, and other tools used to study biological processes and protein interactions.
• Material Science Precursor: Employed in the synthesis of organic electronic materials, such as ligands for OLEDs or conductive polymers, due to its electron-deficient heterocyclic structure.
• Cross-Coupling Reactions: The aldehyde functional group makes it an excellent substrate for Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions to create diverse compound libraries.
• Medicinal Chemistry Scaffold Diversification: Used to introduce the 7-azaindole pharmacophore, known for its hydrogen-bonding capabilities, into lead compounds for improved binding affinity and selectivity.

Basic Information

Product Name	6-Fluoro-7-Azaindole-3-Carboxaldehyde
CAS No.	1190314-77-2
Molecular Formula	C8H5FN2O
Molecular Weight	164.14 g/mol
Synonyms	6-Fluoro-1H-pyrrolo[2,3-b]pyridine-3-carboxaldehyde; 6-Fluoro-7-azaindole-3-carbaldehyde; 3-Formyl-6-fluoro-1H-pyrrolo[2,3-b]pyridine; 6-Fluoro-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde; 6-Fluoro-7-aza-indole-3-carboxaldehyde; 6-Fluoro-7-azaindole-3-aldehyde; 6-Fluoro-1H-pyrrolo[2,3-b]pyridine-3-carboxaldehyde; 6-Fluoro-7-azaindole-3-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 6-Fluoro-7-Azaindole-3-Carboxaldehyde is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our analytical methods, including HPLC, NMR, and MS, are validated to provide reliable specifications for our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.