Description

4-Amino-5-Fluoro-7-Azaindole is a high-purity, heterocyclic organic compound featuring a strategically functionalized azaindole core. This advanced pharmaceutical intermediate is critical for the synthesis of targeted kinase inhibitors and other bioactive molecules, offering a precise building block for medicinal chemistry research and development. It is essential for pharmaceutical R&D teams and fine chemical manufacturers focused on developing novel therapeutics in oncology and other disease areas.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of small-molecule drugs, particularly kinase inhibitors.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Reagent: Serves as a precursor or reference standard in biochemical assays and pharmacological studies.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct complex, nitrogen-containing heterocycles.
• Contract Research & Manufacturing (CRAM): Supplied to organizations engaged in custom synthesis and process development for clinical candidates.
• Academic Research: Utilized in university and institutional labs for exploratory research in organic and medicinal chemistry.

Basic Information

Product Name	4-Amino-5-Fluoro-7-Azaindole
CAS No.	1190310-08-7
Molecular Formula	C7H6FN3
Molecular Weight	151.14 g/mol
Synonyms	4-Amino-5-fluoro-1H-pyrrolo[2,3-b]pyridine; 5-Fluoro-4-amino-7-azaindole; 5-Fluoro-1H-pyrrolo[2,3-b]pyridin-4-amine; 4-Amino-5-fluoro-7-aza-indole; 1H-Pyrrolo[2,3-b]pyridin-4-amine, 5-fluoro-; 5-Fluoro-4-amino-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 4-Amino-5-Fluoro-7-Azaindole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and residual solvent analysis. A Certificate of Analysis (COA) is supplied with each batch to guarantee compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.