Description

Nsc 66523-D3 CAS NO 1189946-33-5 is a high-purity, deuterated chemical compound primarily used as a stable isotope-labeled internal standard in advanced analytical applications. Its core value lies in enabling precise quantification and method validation in complex matrices, ensuring data accuracy and regulatory compliance. This material is essential for researchers and quality control laboratories in the pharmaceutical, agrochemical, and environmental testing sectors who require reliable reference standards for mass spectrometry (LC-MS/MS, GC-MS).

Application

• Internal Standard for Quantitative Analysis: Used as a deuterated internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS/MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for accurate quantification of its non-deuterated counterpart.
• Metabolite Tracing & Pharmacokinetic Studies: Enables the study of drug metabolism, absorption, distribution, and excretion (ADME) in pharmaceutical R&D.
• Method Development & Validation: Critical for developing and validating robust analytical methods in compliance with ICH, FDA, and EMA guidelines.
• Environmental & Food Safety Testing: Applied in the detection and quantification of trace-level contaminants and residues in environmental samples and food products.
• Biomarker Research: Facilitates the precise measurement of endogenous compounds in clinical and biomedical research for biomarker discovery.
• Quality Control & Assurance: Serves as a certified reference material (CRM) for in-house quality control procedures in manufacturing and testing facilities.

Basic Information

Product Name	Nsc 66523-D3
CAS No.	1189946-33-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	NSC-66523-D3; NSC 66523 deuterated; Deuterated NSC-66523; NSC66523-D3; [2H3]-NSC 66523; 1189946-33-5; Stable Isotope Labeled NSC 66523
EINECS	Contact for details

Quality Control

Our Nsc 66523-D3 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 13C) and Mass Spectrometry, to confirm structural identity, isotopic purity (D-enrichment), and chemical purity. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, ensuring traceability and compliance with your research or quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98.0 atom % D
Chemical Purity (by HPLC)	≥ 95.0%
Residual Solvent (GC)	Complies with ICH limits
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.