Description

Prochlorperazine Sulfoxide-D3 is a high-purity, deuterium-labeled internal standard critical for modern analytical chemistry. This compound is essential for ensuring the accuracy and reliability of quantitative analyses in complex matrices. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and quality control facilities for precise method development and validation.

Application

• Internal Standard for LC-MS/MS: Used for the accurate quantification of prochlorperazine and its metabolites in pharmacokinetic and bioanalytical studies.
• Pharmaceutical Impurity Profiling: Aids in the identification and measurement of sulfoxide-related impurities during drug substance and product stability testing.
• Metabolite Research: Serves as a reference standard in the investigation of metabolic pathways and the characterization of oxidative metabolites.
• Method Development & Validation: Critical for developing robust, sensitive, and specific analytical methods in compliance with ICH and FDA guidelines.
• Forensic & Clinical Toxicology: Enables precise measurement in forensic analysis and therapeutic drug monitoring (TDM) applications.
• Quality Control (QC) Testing: Ensures batch-to-batch consistency and purity verification of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Prochlorperazine Sulfoxide-D3
CAS No.	1189943-37-0
Molecular Formula	C₂₀H₂₁D₃ClN₃OS
Molecular Weight	377.93 g/mol
Synonyms	2-Chloro-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine 5-Oxide-d3; Prochlorperazine-d3 Sulfoxide; Deuterated Prochlorperazine Sulfoxide; Prochlorperazine Sulfoxide (trideuterated); Compazine Sulfoxide-d3; 10H-Phenothiazine-10-propanamine, 2-chloro-N,N-dimethyl-, 5-oxide-d3; Internal Standard for Prochlorperazine Sulfoxide
EINECS	Contact for details

Quality Control

Our Prochlorperazine Sulfoxide-D3 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to confirm identity, chemical purity, and isotopic enrichment. We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing all test results and confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D3)	≥ 98.0 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.