Description

5-Fluoro-6-Hydroxypicolinic Acid is a high-purity, multifunctional heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a critical precursor in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique substitution pattern enables precise molecular modifications. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating complex molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Development: Used in the research and production of advanced herbicides and fungicides, leveraging its fluorine and hydroxyl functional groups.
• Ligand Synthesis: Serves as a precursor for creating complex chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Material Science Research: Utilized as a monomer or functional additive in the development of specialty polymers with specific electronic or binding properties.

Basic Information

Product Name	5-Fluoro-6-Hydroxypicolinic Acid
CAS No.	1189757-55-8
Molecular Formula	C6H4FNO3
Molecular Weight	157.10 g/mol
Synonyms	6-Hydroxy-5-fluoropyridine-2-carboxylic Acid; 5-Fluoro-6-hydroxy-2-pyridinecarboxylic Acid; 5-Fluoro-6-hydroxypicolinate; 2-Pyridinecarboxylic acid, 5-fluoro-6-hydroxy-; 5-Fluoro-6-hydroxypyridine-2-carboxylic Acid
EINECS	Contact for details

Quality Control

Our 5-Fluoro-6-Hydroxypicolinic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment, ensuring full traceability and compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.