Description

n-Methyl-3,3-Diphenylpropylamine-D3 is a deuterated analog of a key pharmaceutical intermediate, where specific hydrogen atoms are replaced with the stable isotope deuterium. This deuteration is critical for enhancing metabolic stability and pharmacokinetic profiles in drug development, making it a valuable tool for creating deuterated drug candidates. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for applications in medicinal chemistry and advanced pharmacokinetic studies.

Application

• Deuterated Drug Development: Serves as a crucial building block for synthesizing deuterium-labeled pharmaceutical compounds to improve drug metabolism and extend half-life.
• Metabolic Pathway Tracing: Used as a stable isotope-labeled internal standard in mass spectrometry for accurate quantification and metabolic studies.
• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex, high-value active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Enables structure-activity relationship (SAR) studies by providing a deuterated version of a core amine structure.
• Reference Standard Production: Manufactured to high purity for use as a certified reference material (CRM) in analytical laboratories.

Basic Information

Product Name	n-Methyl-3,3-Diphenylpropylamine-D3
CAS No.	1189699-37-3
Molecular Formula	C₁₆H₁₇D₃N
Molecular Weight	~229.35 g/mol
Synonyms	3,3-Diphenyl-N-methylpropylamine-D3; N-Methyl-3,3-diphenyl-1-propanamine-D3; 1-Propanamine, N-methyl-3,3-diphenyl-, D3-labeled; Deuteronated N-Methyl-3,3-Diphenylpropylamine; N-Methyl-γ,γ-diphenylpropylamine-D3; Deuterated Diphenylpropylamine Derivative; (3,3-Diphenylpropyl)(methyl)amine-D3
EINECS	Contact for details

Quality Control

Our n-Methyl-3,3-Diphenylpropylamine-D3 is manufactured under strict quality systems to ensure batch-to-batch consistency and high isotopic purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as chemical purity, isotopic enrichment (D-content), and impurity profiles. We adhere to cGMP principles for advanced pharmaceutical intermediates, and specifications can be aligned with client requirements for research or commercial development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.