Description

2,5-Pyridinedicarbonyl Acid-13C7 is a high-purity, isotopically labeled derivative of 2,5-pyridinedicarboxylic acid, where seven carbon atoms are replaced with the stable isotope carbon-13. This compound is essential as a critical internal standard and precursor in quantitative mass spectrometry and metabolic pathway analysis, ensuring unparalleled accuracy in trace-level detection. It is primarily required by pharmaceutical research laboratories, contract research organizations (CROs), and advanced material scientists working on drug metabolism and pharmacokinetics (DMPK) studies, proteomics, and the development of novel labeled compounds.

Application

• Internal Standard for LC-MS/MS: Used as a quantitative reference standard in bioanalytical method development for accurate measurement of pyridine-dicarboxylate analogs in complex biological matrices.
• Metabolic Pathway Tracing: Serves as a labeled precursor in 13C-isotope labeling studies to elucidate metabolic fluxes and mechanisms in biochemical research.
• Pharmaceutical Impurity Profiling: Employed in the identification and quantification of process-related impurities and degradation products in active pharmaceutical ingredients (APIs).
• Stable Isotope Labeled Compound Synthesis: Acts as a key building block for the synthesis of more complex 13C-labeled molecules for research and diagnostic applications.
• NMR Spectroscopy: Provides a valuable tool for nuclear magnetic resonance (NMR) studies due to its enriched 13C nuclei, aiding in structural elucidation.

Basic Information

Product Name	2,5-Pyridinedicarbonyl Acid-13C7
CAS No.	1189695-39-3
Molecular Formula	13C7H5NO4
Molecular Weight	~199.09 (for 13C7)
Synonyms	2,5-Pyridinedicarboxylic Acid-13C7; Isocinchomeronic Acid-13C7; 2,5-Dicarboxypyridine-13C7; Pyridine-2,5-dicarboxylic Acid-13C7; 13C7-Isocinchomeronic Acid; 2,5-Pyridinedicarboxylic Acid (13C7); 1189695-39-3
EINECS	Contact for details

Quality Control

Every batch of 2,5-Pyridinedicarbonyl Acid-13C7 is manufactured and analyzed under strict quality management systems. We guarantee high isotopic purity and chemical purity to meet the exacting demands of analytical and synthetic applications. Comprehensive testing includes isotopic enrichment analysis by mass spectrometry, chemical purity by HPLC, and identity confirmation. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (13C)	≥ 99 atom % 13C
Isotopic Enrichment	≥ 99% 13C7
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.