Description

(S)-Gossypol (Acetic Acid) CAS NO 1189561-66-7 is a specific enantiomer of the naturally occurring polyphenolic compound, gossypol, isolated from cotton plants. This high-purity chiral form is of significant interest in advanced pharmaceutical research and development due to its distinct biological activity profile compared to the racemic mixture. It is primarily sought after by researchers and developers in the life sciences sector for its potential as a key intermediate or active pharmaceutical ingredient (API) in targeted therapeutic applications.

Application

• Pharmaceutical Research & Development: As a key chiral intermediate or reference standard in the synthesis and study of novel therapeutic agents.
• Oncology Research: Investigation of its enantiomer-specific anti-proliferative and pro-apoptotic effects on various cancer cell lines.
• Biochemical Research: Used as a specific inhibitor or modulator in enzymatic and receptor-binding studies to understand biological pathways.
• API Development: Serves as the active pharmaceutical ingredient in pre-clinical and clinical-stage formulations for targeted diseases.
• Analytical Standard: Employed as a high-purity certified reference material (CRM) for method development and quality control in analytical laboratories.
• Asymmetric Synthesis: Utilized as a chiral building block or ligand in the synthesis of complex, enantiomerically pure molecules.

Basic Information

Product Name	(S)-Gossypol (Acetic Acid)
CAS No.	1189561-66-7
Molecular Formula	C32H34O10 (for gossypol acetic acid complex)
Molecular Weight	578.61 g/mol (for gossypol acetic acid complex)
Synonyms	(S)-(-)-Gossypol Acetic Acid; (-)-Gossypol Acetic Acid; (S)-Gossypol Acetate; Gossypol, (S)-, compound with acetic acid (1:1); 1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)-[2,2'-binaphthalene]-8,8'-dicarboxaldehyde, (S)-, compound with acetic acid (1:1); AT-101 (S-enantiomer); Bcl-2 Inhibitor (S)-enantiomer
EINECS	Contact for details

Quality Control

Our (S)-Gossypol (Acetic Acid) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for research and pharmaceutical use. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profiles is supplied with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to brownish-yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (S)-enantiomer
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.