Description

3-Bromo-5-Fluoropyridine-2-Carboxylic Acid is a high-value, multi-functional heterocyclic building block essential for modern synthetic chemistry. This compound is specifically engineered to serve as a critical precursor in the development of advanced pharmaceutical intermediates and agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyridine and halogen motifs.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as ligands for OLEDs or molecular sensors, due to its functionalized aromatic system.
• Custom Synthesis and Contract Manufacturing: An important building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-Bromo-5-Fluoropyridine-2-Carboxylic Acid
CAS No.	1189513-55-0
Molecular Formula	C6H3BrFNO2
Molecular Weight	220.00 g/mol
Synonyms	2-Bromo-6-fluoro-3-pyridinecarboxylic acid; 5-Fluoro-3-bromopyridine-2-carboxylic acid; 3-Bromo-5-fluoropicolinic acid; 2-Carboxy-3-bromo-5-fluoropyridine; 1189513-55-0; 3-Br-5-F-2-PyCOOH
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Fluoropyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity building blocks for GMP and non-GMP development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.