Description

1-(6-Bromopyridin-3-Yl)-2,2,2-Trifluoroethanol is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a bromo-substituted pyridine ring and a trifluoroethanol moiety, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with specific electronic or surface properties.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological systems and mechanisms.

Basic Information

Product Name	1-(6-Bromopyridin-3-Yl)-2,2,2-Trifluoroethanol
CAS No.	1188477-81-7
Molecular Formula	C7H5BrF3NO
Molecular Weight	256.02 g/mol
Synonyms	2,2,2-Trifluoro-1-(6-bromopyridin-3-yl)ethanol; 1-(6-Bromo-3-pyridinyl)-2,2,2-trifluoroethanol; 3-Pyridinemethanol, 6-bromo-α-(trifluoromethyl)-; 6-Bromo-α-(trifluoromethyl)-3-pyridinemethanol; (6-Bromopyridin-3-yl)(trifluoromethyl)methanol
EINECS	Contact for details

Quality Control

Our 1-(6-Bromopyridin-3-Yl)-2,2,2-Trifluoroethanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.