Description

2-Amino-5-Fluoro-Pyridine-3-Carbaldehyde is a high-purity fluorinated pyridine derivative, serving as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both an amino and an aldehyde functional group on a fluorinated pyridine ring, makes it an indispensable intermediate for constructing complex heterocyclic systems. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluoropyridine scaffold.
• Material Science: Serves as a building block for creating functionalized ligands, organic semiconductors, and advanced polymers with specific electronic properties.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions, Schiff base formation, and other transformations to create complex molecular architectures.
• Research & Development: Essential for medicinal chemistry programs and academic research focused on heterocyclic chemistry and fluorine chemistry.

Basic Information

Product Name	2-Amino-5-Fluoro-Pyridine-3-Carbaldehyde
CAS No.	1188433-88-6
Molecular Formula	C6H5FN2O
Molecular Weight	140.12 g/mol
Synonyms	5-Fluoro-2-aminopyridine-3-carboxaldehyde; 3-Formyl-5-fluoro-2-aminopyridine; 2-Amino-5-fluoronicotinaldehyde; 5-Fluoro-2-amino-3-pyridinecarboxaldehyde; 1188433-88-6; 2-Amino-5-fluoropyridine-3-carboxaldehyde; 5-Fluoro-2-aminopyridine-3-carbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-5-Fluoro-Pyridine-3-Carbaldehyde is manufactured and tested under strict quality management protocols. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and cGMP manufacturing. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by HPLC, NMR, and MS.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.