Description

7-Fluoro-4,4-Dimethyl-1,2,3,4-Tetrahydro-Quinoline is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic introduction of fluorine and the rigid, substituted tetrahydroquinoline scaffold, which are critical for modulating the physicochemical and biological properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients with enhanced metabolic stability, bioavailability, and target selectivity.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the fluorine atom improves lipophilicity and environmental stability.
• Material Science Research: Serves as a precursor for functionalized organic materials, including ligands for catalysis and components for organic electronics.
• Chemical Biology Probes: Employed in the synthesis of fluorinated probes and tags for studying biological processes and protein interactions.
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry and for custom synthesis projects.

Basic Information

Product Name	7-Fluoro-4,4-Dimethyl-1,2,3,4-Tetrahydro-Quinoline
CAS No.	1187933-43-2
Molecular Formula	C11H14FN
Molecular Weight	179.24 g/mol
Synonyms	7-Fluoro-4,4-dimethyl-1,2,3,4-tetrahydroquinoline; 4,4-Dimethyl-7-fluoro-1,2,3,4-tetrahydroquinoline; 1,2,3,4-Tetrahydro-7-fluoro-4,4-dimethylquinoline; 7-Fluoro-4,4-dimethyl-3,4-dihydro-2H-quinoline; 7-Fluoro-4,4-dimethyl-1,2,3,4-tetrahydroquinoline (CAS 1187933-43-2)
EINECS	Contact for details

Quality Control

Our 7-Fluoro-4,4-Dimethyl-1,2,3,4-Tetrahydro-Quinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We support cGMP compliance for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.