Description

Ethyl 3-Fluoropyridine-2-Carboxylate is a high-purity fluorinated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role in introducing the 3-fluoro-2-carboxylate motif, a valuable scaffold for modulating the biological activity and physicochemical properties of target molecules. Pharmaceutical, agrochemical, and material science researchers need it for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Building block for developing new-generation herbicides and pesticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Used to create specialized ligands for metal catalysis and organocatalysts in asymmetric synthesis.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of fluorinated probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects and scale-up activities.

Basic Information

Product Name	Ethyl 3-Fluoropyridine-2-Carboxylate
CAS No.	1187732-69-9
Molecular Formula	C8H8FNO2
Molecular Weight	169.15 g/mol
Synonyms	Ethyl 3-Fluoro-2-pyridinecarboxylate; 3-Fluoropyridine-2-carboxylic Acid Ethyl Ester; 2-Carbethoxy-3-fluoropyridine; Ethyl 3-Fluoropicolinate; 3-Fluoro-2-pyridinecarboxylic Acid Ethyl Ester; 1187732-69-9; 3-Fluoropyridine-2-carboxylate ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 3-Fluoropyridine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with complete analytical data are provided for every shipment. We adhere to cGMP principles where applicable to support our clients' regulatory requirements in pharmaceutical and agrochemical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.