Description

6-Methyl-2-(3,4,5-Trifluorobenzoyl)Pyridine is a high-purity fluorinated pyridine derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its unique trifluoromethylbenzoyl-pyridine scaffold, which is essential for modulating the physicochemical and biological properties of target molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, where the fluorine atoms enhance bioavailability and environmental stability.
• Ligand Synthesis: Serves as a precursor for creating complex ligands used in catalysis and material science applications.
• Fluorinated Compound Library: An important reagent for constructing diverse fluorinated compound libraries for high-throughput screening in drug discovery.
• Chemical Biology Probes: Utilized in the design of molecular probes to study biological processes and enzyme mechanisms.

Basic Information

Product Name	6-Methyl-2-(3,4,5-Trifluorobenzoyl)Pyridine
CAS No.	1187166-15-9
Molecular Formula	C14H9F3NO
Molecular Weight	264.22 g/mol
Synonyms	2-(3,4,5-Trifluorobenzoyl)-6-picoline; 6-Methyl-2-(3,4,5-trifluorobenzoyl)pyridine; 2-(3,4,5-Trifluorobenzoyl)-6-methylpyridine; 3,4,5-Trifluoro-2-pyridin-2-ylphenyl methanone (tautomeric form); 6-Methyl-2-(3,4,5-trifluorophenyl)(pyridin-2-yl)methanone
EINECS	Contact for details

Quality Control

Our 6-Methyl-2-(3,4,5-Trifluorobenzoyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.