Description

5-(4-Bromo-2-Fluorophenyl)-2-Methylpyridine is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its unique molecular architecture, which incorporates halogen and fluorine substituents on a biphenyl-pyridine scaffold, enabling precise molecular modifications. This compound is primarily needed by R&D and process chemistry teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Serves as a critical scaffold for developing new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Used in the research and development of organic electronic materials, such as ligands for OLEDs and charge-transport materials.
• Chemical Biology: Employed as a probe or linker in the design of molecular tools for studying biological pathways and protein interactions.
• Custom Synthesis: An essential starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.
• Ligand Synthesis: Useful for constructing complex ligands in catalysis and coordination chemistry research.

Basic Information

Product Name	5-(4-Bromo-2-Fluorophenyl)-2-Methylpyridine
CAS No.	1187163-44-5
Molecular Formula	C12H9BrFN
Molecular Weight	266.11 g/mol
Synonyms	2-Methyl-5-(4-bromo-2-fluorophenyl)pyridine; 5-(4-Bromo-2-fluorophenyl)-2-picoline; 4-Bromo-2-fluoro-5-(2-methylpyridin-5-yl)benzene; 2-Fluoro-4-bromo-5-(2-methyl-5-pyridyl)benzene; 5-(4-Bromo-2-fluorophenyl)-2-methylpyridine; 2-Methyl-5-(4'-bromo-2'-fluorophenyl)pyridine
EINECS	Contact for details

Quality Control

Our 5-(4-Bromo-2-Fluorophenyl)-2-Methylpyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.