Description

5-Fluoro-3-Iodo-Pyridin-2-Ol is a halogenated pyridine derivative, a versatile and high-value building block in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides, fungicides, and insecticides, where the halogen atoms enable fine-tuning of biological activity.
• Material Science Research: Used in the synthesis of functionalized ligands for catalysis and in the development of organic electronic materials.
• Cross-Coupling Reactions: The iodine atom provides an excellent handle for versatile palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create complex biaryl structures.
• Chemical Biology Probes: Employed as a building block for creating molecular probes and tags used in biochemical and diagnostic research.

Basic Information

Product Name	5-Fluoro-3-Iodo-Pyridin-2-Ol
CAS No.	1186311-05-6
Molecular Formula	C5H3FINO
Molecular Weight	254.99 g/mol
Synonyms	2-Hydroxy-5-fluoro-3-iodopyridine; 3-Iodo-5-fluoropyridin-2-ol; 5-Fluoro-3-iodopyridin-2(1H)-one; 5-Fluoro-3-iodo-2-pyridinol; 5-Fluoro-3-iodo-2-hydroxypyridine; 1186311-05-6; 2-Pyridinol, 5-fluoro-3-iodo-
EINECS	Contact for details

Quality Control

Our 5-Fluoro-3-Iodo-Pyridin-2-Ol is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, meeting the exacting standards of research and process chemistry. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant quality management systems to guarantee reliable supply and technical data integrity for our global customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.