Description

(5-Fluorofuro[2,3-B]Pyridin-2-Yl)Methanol is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is of significant commercial interest for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of targeted therapies, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, especially those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the creation of new chemical entities (NCEs) in drug discovery.
• API Development: Used in the pilot-scale and commercial-scale production of active pharmaceutical ingredients requiring a fluorinated furopyridine moiety.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis projects and process development.
• Biochemical Reagent: Potential use as a specialized reagent or inhibitor in biochemical assays and proteomics research.

Basic Information

Product Name	(5-Fluorofuro[2,3-B]Pyridin-2-Yl)Methanol
CAS No.	1186310-91-7
Molecular Formula	C9H6FNO2
Molecular Weight	179.15 g/mol
Synonyms	2-(Hydroxymethyl)-5-fluorofuro[2,3-b]pyridine; 5-Fluoro-2-(hydroxymethyl)furo[2,3-b]pyridine; (5-Fluorofuro[2,3-b]pyridin-2-yl)methanol; 5-Fluoro-2-furo[2,3-b]pyridinemethanol
EINECS	Contact for details

Quality Control

Our (5-Fluorofuro[2,3-B]Pyridin-2-Yl)Methanol is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.