Description

Dalantercept CAS NO 1186210-24-1 is a high-purity, biologically active small molecule compound of significant interest in pharmaceutical research and development. Its primary value lies in its targeted mechanism of action, making it a critical reagent for investigating specific biochemical pathways. This product is essential for researchers and developers in the biotechnology and pharmaceutical industries, particularly those focused on oncology and targeted therapeutic discovery.

Application

• Pharmaceutical Research & Development (R&D): Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the discovery and preclinical testing of novel therapeutics.
• Biochemical Pathway Analysis: Used as a selective tool compound in in vitro and cell-based assays to study and validate specific molecular targets and signaling cascades.
• Oncology Drug Discovery: A vital component in screening libraries and developing potential anti-cancer agents due to its targeted biological activity.
• Academic Research: Employed in university and institutional laboratories for fundamental studies in cell biology, pharmacology, and medicinal chemistry.
• Contract Research Organization (CRO) Services: Supplied to CROs conducting client-sponsored drug discovery and toxicity studies.
• Analytical Method Development: Used as a known standard for developing and validating HPLC, LC-MS, and other analytical methods for purity and potency assessment.

Basic Information

Product Name	Dalantercept
CAS No.	1186210-24-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	ACE-041; Dalantercept (ACE-041); Recombinant fusion protein ACE-041; Activin receptor-like kinase 1 (ALK1) Fc fusion protein; ALK1-Fc; PF-03446962 (related development code)
EINECS	Contact for details

Quality Control

Our Dalantercept is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation, purity assessment, and biological activity evaluation, to ensure it meets the stringent requirements for research-grade biomolecules. A detailed Certificate of Analysis (COA) documenting purity, potency, endotoxin levels, and sterility (where applicable) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Biological Activity (Cell-based assay)	Contact for details
Endotoxin	< 1.0 EU/mg
Moisture Content (KF)	< 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.