Description

1-(1',1'-Difluoropropyl)-4-Methylbenzene is a specialized fluorinated aromatic compound, identified by CAS number 1186194-63-7, serving as a valuable building block in advanced organic synthesis. Its core value lies in the strategic incorporation of fluorine atoms and a propyl chain, which can significantly alter the physicochemical properties of target molecules, enhancing their metabolic stability, lipophilicity, and bioavailability. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the difluoropropyl moiety can improve product efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated organic semiconductors and liquid crystal compounds for electronic displays.
• Polymer & Material Science: Acts as a monomer or modifier in the production of specialty polymers with enhanced chemical resistance, thermal stability, or unique surface properties.
• Fluorine Chemistry Research: A valuable reagent for studying structure-activity relationships (SAR) and developing new fluorination methodologies in academic and industrial laboratories.

Basic Information

Product Name	1-(1',1'-Difluoropropyl)-4-Methylbenzene
CAS No.	1186194-63-7
Molecular Formula	C10H12F2
Molecular Weight	170.20 g/mol
Synonyms	1-(1,1-Difluoropropyl)-4-methylbenzene; p-Methyl-α,α-difluoropropylbenzene; 4-Methyl-1-(1,1-difluoropropyl)benzene; 1-Methyl-4-(1,1-difluoropropyl)benzene; 1,1-Difluoropropyl-4-methylbenzene; DFPMB; (1,1-Difluoropropyl)toluene
EINECS	Contact for details

Quality Control

Our 1-(1',1'-Difluoropropyl)-4-Methylbenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring material traceability and reliable performance in critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong alkalis and other incompatible materials. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.