Description

3-Chloropyridine-2-Sulfonyl Chloride is a high-purity, reactive organosulfur building block essential for advanced chemical synthesis. Its dual functionality as a sulfonyl chloride and a halogenated heterocycle makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides with specific modes of action.
• Material Science Research: Serves as a precursor for functional polymers, ligands for metal-organic frameworks (MOFs), and specialty chemicals.
• Chemical Biology Probes: Employed in the development of activity-based probes and covalent inhibitors for target identification and validation.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-Chloropyridine-2-Sulfonyl Chloride
CAS No.	1186049-79-5
Molecular Formula	C5H3Cl2NO2S
Molecular Weight	212.05 g/mol
Synonyms	2-Chlorosulfonyl-3-chloropyridine; 3-Chloro-2-pyridinesulfonyl chloride; 3-Chloropyridine-2-sulphonyl chloride; 2-Pyridinesulfonyl chloride, 3-chloro-; 3-Chloro-2-pyridylsulfonyl chloride; 3-Chloropyridine-2-sulfonylchloride; 3-Chloro-2-sulfonylchloridopyridine
EINECS	Contact for details

Quality Control

Our 3-Chloropyridine-2-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.