Description

3-Hydroxy-2-Methylpyridine-D3 is a deuterated derivative of 3-hydroxy-2-methylpyridine, a key pyridine-based building block. This compound is specifically valued for its use as a stable isotope-labeled internal standard in analytical chemistry, enabling precise quantification and method development. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and analytical reference material sectors who require high-purity, isotopically labeled compounds for mass spectrometry and metabolic studies.

Application

• Internal Standard for LC-MS/MS: Used as a deuterium-labeled standard for the accurate quantification of 3-hydroxy-2-methylpyridine and related metabolites in complex biological matrices.
• Pharmaceutical Research: Employed in drug metabolism and pharmacokinetics (DMPK) studies to track the absorption, distribution, metabolism, and excretion of pharmaceutical compounds.
• Metabolite Synthesis: Serves as a precursor or intermediate in the synthesis of deuterated metabolites for use as certified reference materials.
• Analytical Method Development: Critical for developing and validating highly sensitive and specific analytical methods in bioanalytical laboratories.
• Isotope Dilution Mass Spectrometry (IDMS): Provides the high isotopic purity required for this gold-standard quantitative analytical technique.
• Agrochemical Research: Used in environmental fate studies and residue analysis of pyridine-based pesticides and herbicides.

Basic Information

Product Name	3-Hydroxy-2-Methylpyridine-D3
CAS No.	1185315-05-2
Molecular Formula	C6H4D3NO
Molecular Weight	113.15 g/mol
Synonyms	2-Methyl-3-hydroxypyridine-d3; 3-Hydroxy-2-picoline-d3; 3-Pyridinol, 2-methyl-d3; Deuteronated 3-Hydroxy-2-methylpyridine; 2-Methyl-3-pyridinol-d3; 3-Hydroxy-2-methylpyridine (methyl-d3); 3-Hydroxy-2-(trideuteriomethyl)pyridine
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-2-Methylpyridine-D3 is produced under strict quality management systems to ensure batch-to-batch consistency and high isotopic purity. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and impurity profile is provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.