Description

Caffeic Acid-13C3 is a stable isotope-labeled analog of the naturally occurring phenolic compound, caffeic acid, where three carbon atoms are replaced with the 13C isotope. This product is essential for use as an internal standard in quantitative mass spectrometry, enabling precise and accurate measurement of caffeic acid and its metabolites in complex biological matrices. It is a critical tool for researchers and quality control laboratories in the pharmaceutical, nutraceutical, and food science industries, particularly for pharmacokinetic studies, metabolic pathway analysis, and authenticity testing of natural products.

Application

• Quantitative Mass Spectrometry (MS) Internal Standard: Primary use for accurate quantification of caffeic acid in LC-MS/MS and GC-MS applications.
• Pharmacokinetic and Drug Metabolism Studies (DMPK): Tracing the absorption, distribution, metabolism, and excretion (ADME) of caffeic acid and related drug candidates.
• Biomedical and Clinical Research: Investigating the role of caffeic acid in antioxidant activity, inflammation, and other biochemical pathways.
• Food and Beverage Analysis: Authenticity testing, quality control, and quantification of caffeic acid in wines, coffees, fruits, and herbal extracts.
• Nutraceutical and Cosmetic Product Development: Supporting stability testing and bio-efficacy studies of products containing caffeic acid derivatives.
• Environmental and Agricultural Science: Studying plant metabolism and the environmental fate of phenolic compounds.

Basic Information

Product Name	Caffeic Acid-13C3
CAS No.	1185245-82-2
Molecular Formula	C9H8O4 (with three 13C atoms)
Molecular Weight	~183.1 g/mol (exact mass depends on isotopic enrichment)
Synonyms	(2E)-3-(3,4-Dihydroxyphenyl)-2-propenoic-13C3 acid; 3,4-Dihydroxycinnamic-13C3 acid; 13C3-Caffeic Acid; Caffeic Acid (13C3); Isotopically Labeled Caffeic Acid; [13C3]-Caffeic Acid; CA-13C3; Stable Isotope-Labeled Internal Standard (SIL-IS) for Caffeic Acid
EINECS	Contact for details

Quality Control

Every batch of Caffeic Acid-13C3 is manufactured and analyzed under strict quality protocols to ensure the highest isotopic and chemical purity for sensitive analytical applications. Our quality commitment includes verification of isotopic enrichment (atom % 13C), chemical purity by HPLC, and confirmation of structure by NMR and MS. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is easily oxidized and light-sensitive; handling should minimize exposure to air and ambient light.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C (on three labeled positions)
Chemical Purity	≥ 95% (by HPLC, area%)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.