Description

5-[4-[2-((Methyl-D3)Pyridin-2-Ylamino)Ethoxy]Benzylidene]Thiazolidine-2,4-Dione is a high-purity, deuterated chemical reference standard with a specific molecular structure. This compound is of significant value for pharmaceutical research and development, particularly in the study of metabolic pathways and drug efficacy. It is primarily required by research institutions, pharmaceutical companies, and contract research organizations (CROs) engaged in advanced analytical chemistry, pharmacokinetics, and the development of novel therapeutic agents.

Application

• Pharmaceutical Reference Standard: Used as an internal standard or calibrant in quantitative analytical methods such as LC-MS and HPLC for accurate drug quantification.
• Metabolic Studies: Employed in drug metabolism and pharmacokinetics (DMPK) research to trace and understand the biotransformation of parent drug molecules.
• Isotope-Labeled Intermediate: Serves as a critical building block in the synthesis of more complex deuterated compounds for clinical research and development.
• Biomarker Research: Facilitates the development and validation of assays for detecting specific analytes in complex biological matrices.
• Quality Control in API Manufacturing: Acts as a high-purity standard to ensure the quality and consistency of active pharmaceutical ingredient (API) batches.
• Academic Research: Utilized in university and institutional labs for fundamental research in medicinal chemistry and organic synthesis.

Basic Information

Product Name	5-[4-[2-((Methyl-D3)Pyridin-2-Ylamino)Ethoxy]Benzylidene]Thiazolidine-2,4-Dione
CAS No.	1185245-57-1
Molecular Formula	C18H15D3N3O3S
Molecular Weight	369.42 g/mol
Synonyms	5-[[4-[2-[(Methyl-d3)-2-pyridinylamino]ethoxy]phenyl]methylene]-2,4-thiazolidinedione; Deuterated TZD Derivative; (Methyl-d3)-Labelled Thiazolidinedione; 5-(4-(2-((Methyl-d3)pyridin-2-ylamino)ethoxy)benzylidene)thiazolidine-2,4-dione; 1185245-57-1; Deuterium Labeled PPARγ Ligand Analog; CD3-Labeled Thiazolidinedione
EINECS	Contact for details

Quality Control

Our 5-[4-[2-((Methyl-D3)Pyridin-2-Ylamino)Ethoxy]Benzylidene]Thiazolidine-2,4-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and MS, to ensure high chemical and isotopic purity suitable for research applications. Certificates of Analysis (COA) with detailed chromatographic data and spectral information are provided to guarantee traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium, D)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.