Description

4-{[(p-Fluorophenyl)Imino]Methyl}Phenol-D4 is a deuterated derivative of a Schiff base compound, where four hydrogen atoms are replaced with deuterium, serving as a stable isotope-labeled internal standard. This high-purity labeled compound is critical for ensuring accuracy and reliability in quantitative analytical methods, particularly mass spectrometry. It is primarily utilized by research institutions and pharmaceutical companies engaged in advanced analytical chemistry, metabolism studies, and the development of deuterated drug candidates.

Application

• Internal Standard for LC-MS/MS: Essential for precise quantification in bioanalytical assays for pharmacokinetic and metabolomic studies.
• Metabolic Pathway Tracing: Used in drug metabolism and disposition (DMPK) research to track and identify metabolites.
• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for method development and validation in QA/QC laboratories.
• Deuterated Drug Synthesis: Acts as a key synthetic intermediate or precursor in the development of deuterium-labeled pharmaceuticals.
• Stable Isotope Labeling: Employed in various spectroscopic techniques (NMR, IR) for mechanistic and structural analysis.

Basic Information

Product Name	4-{[(p-Fluorophenyl)Imino]Methyl}Phenol-D4
CAS No.	1185243-77-9
Molecular Formula	C14H7D4FNO
Molecular Weight	~232.25 g/mol
Synonyms	4-[(4-Fluorophenylimino)methyl]phenol-d4; p-[(p-Fluorophenylimino)methyl]phenol-d4; (4-Hydroxybenzylidene)-(4-fluorophenyl)amine-d4; Deuterated Schiff Base Derivative; 4-Fluorobenzylidene-4-hydroxyaniline-d4; 4-[(E)-(4-Fluorophenyl)iminomethyl]phenol-d4; N-(4-Hydroxybenzylidene)-4-fluoroaniline-d4
EINECS	Contact for details

Quality Control

Every batch of 4-{[(p-Fluorophenyl)Imino]Methyl}Phenol-D4 is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to support its use as a high-grade reference material. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing isotopic purity, chemical purity, and identity confirmation are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.