Description

4'-Tosyl Mycophenolic Acid-D3 is a deuterated derivative of mycophenolic acid, a key intermediate in pharmaceutical research and development. This compound is specifically designed for use as an internal standard in quantitative bioanalytical methods, such as LC-MS/MS, ensuring high accuracy and precision in pharmacokinetic and metabolic studies. It is an essential tool for researchers and quality control laboratories in the pharmaceutical and biotechnology sectors, particularly those focused on immunosuppressant drug development and therapeutic drug monitoring.

Application

• Primary use as a stable isotope-labeled internal standard for the quantification of mycophenolic acid and its metabolites in biological matrices.
• Critical component in LC-MS/MS method development and validation for clinical and preclinical studies.
• Enhances data reliability in pharmacokinetic (PK) and pharmacodynamic (PD) research for immunosuppressive therapies.
• Supports therapeutic drug monitoring (TDM) programs to optimize patient dosing regimens.
• Used in metabolite identification and profiling studies due to its isotopic purity.
• Valuable for impurity characterization and reference standard synthesis in pharmaceutical quality control.

Basic Information

Product Name	4'-Tosyl Mycophenolic Acid-D3
CAS No.	1185242-13-0
Molecular Formula	C24H20D3NO7S
Molecular Weight	Approx. 478.53 g/mol
Synonyms	Mycophenolic Acid 4'-Tosyl-D3; Mycophenolic Acid 4'-Tosyl Ester-D3; 4'-O-Tosylmycophenolic Acid-d3; (E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoic Acid 4'-Tosyl Ester-d3; 4'-Tosyl MPA-D3; Deuterated 4'-Tosyl Mycophenolic Acid; 1185242-13-0; 4'-Tosylmycophenolic Acid Deuterated Standard
EINECS	Contact for details

Quality Control

Our 4'-Tosyl Mycophenolic Acid-D3 is manufactured under strict quality systems to ensure the high isotopic and chemical purity required for analytical applications. Each batch is characterized by advanced spectroscopic and chromatographic techniques, including NMR, HPLC, and MS, to confirm identity, isotopic enrichment (typically ≥98 atom % D), and chemical purity (typically ≥95%). A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation. The product is sensitive to light and moisture; handle under appropriate laboratory conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Isotopic Purity (NMR/MS)	≥ 98 atom % D
Chemical Purity	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.