Description

4-(Phenyl-13C6-Amino]-1-Benzyl-4-Piperidinecarboxylic Acid Methyl Ester is a stable isotope-labeled compound, specifically a carbon-13 enriched derivative of a key piperidine-based intermediate. This product is essential for researchers and manufacturers requiring high-purity labeled compounds for quantitative analysis and metabolic pathway tracing. It is primarily utilized in the pharmaceutical and biotechnology sectors for advanced drug discovery, development of analytical reference standards, and sophisticated pharmacokinetic studies.

Application

• Internal Standard for LC-MS/MS: Serves as a critical quantitative standard in liquid chromatography-mass spectrometry for accurate bioanalysis of drug candidates and metabolites.
• Metabolic Pathway Research: Used as a tracer in in vitro and in vivo studies to elucidate drug metabolism and disposition using 13C NMR or mass spectrometry.
• Pharmaceutical Reference Standard: Acts as a certified reference material (CRM) for quality control and method validation in API (Active Pharmaceutical Ingredient) manufacturing.
• Preclinical & Clinical Development: Employed in Absorption, Distribution, Metabolism, and Excretion (ADME) studies during the drug development pipeline.
• Isotope Dilution Mass Spectrometry (IDMS): Provides high-accuracy quantification in complex biological matrices for regulatory and research purposes.
• Synthetic Intermediate: Functions as a building block for the synthesis of more complex 13C-labeled target molecules in medicinal chemistry.

Basic Information

Item	Detail
Product Name	4-(Phenyl-13C6-Amino]-1-Benzyl-4-Piperidinecarboxylic Acid Methyl Ester
CAS No.	1185114-46-8
Molecular Formula	C20H22N2O2 (13C6)
Molecular Weight	~328.4 g/mol (with 13C6 enrichment)
Synonyms	Methyl 1-Benzyl-4-[(phenyl-13C6)amino]piperidine-4-carboxylate; 1-Benzyl-4-[(phenyl-13C6)amino]piperidine-4-carboxylic Acid Methyl Ester; 13C6-Labeled 4-Anilino-1-benzylpiperidine-4-carboxylic Acid Methyl Ester; 4-(13C6-Anilino)-1-benzyl-4-piperidinecarboxylic Acid Methyl Ester; 13C6-4-Anilino-1-benzylpiperidine-4-methyl carboxylate; 1185114-46-8 (CAS Name); Carbon-13 Labeled Piperidine Derivative
EINECS	Contact for details

Quality Control

Every batch of our 4-(Phenyl-13C6-Amino]-1-Benzyl-4-Piperidinecarboxylic Acid Methyl Ester is manufactured and tested under strict quality management systems. We guarantee high chemical and isotopic purity, with comprehensive characterization using NMR (1H, 13C), HPLC, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, isotopic enrichment, and solvent content to meet the stringent requirements of research and regulatory applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere at -20°C to ensure maximum stability of the labeled compound.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (13C NMR/MS)	≥ 99 atom % 13C (at labeled positions)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.