Description

2-Amino-3,8-Dimethylimidazo[4,5-F]Quinoxaline-13C,15N2 is a stable isotope-labeled analog of the heterocyclic aromatic amine (HAA) MeIQx, specifically labeled with carbon-13 and nitrogen-15. This compound is critically important as a high-purity internal standard for advanced analytical chemistry, enabling precise quantification and method validation. It is primarily required by analytical laboratories, research institutions, and pharmaceutical companies engaged in food safety testing, toxicology studies, and metabolic research.

Application

• Quantitative Mass Spectrometry (MS): Serves as an essential internal standard for the accurate LC-MS/MS and GC-MS analysis of MeIQx and related HAAs in complex matrices.
• Food Safety & Contaminant Analysis: Used in the detection and quantification of mutagenic/carcinogenic HAAs formed in cooked meats (beef, chicken, fish) and other thermally processed foods.
• Metabolic & Pharmacokinetic Studies: Enables tracing and precise measurement of MeIQx metabolites in in vitro and in vivo studies to understand absorption, distribution, metabolism, and excretion (ADME).
• Toxicology & Cancer Research: Facilitates research into the genotoxic mechanisms, DNA adduct formation, and carcinogenic potency of dietary HAAs.
• Method Development & Validation: Critical for developing robust, sensitive, and reproducible analytical methods in compliance with guidelines from agencies like FDA, EPA, and ISO.
• Quality Control & Reference Standards: Acts as a certified reference material (CRM) for calibrating instruments and ensuring data integrity in testing laboratories.

Basic Information

Product Name	2-Amino-3,8-Dimethylimidazo[4,5-F]Quinoxaline-13C,15N2
CAS No.	1185023-44-2
Molecular Formula	C1113CH1115N4
Molecular Weight	~216.21 g/mol (for 13C1, 15N2 labeled form)
Synonyms	MeIQx-13C,15N2
2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline-13C,15N2
2-Amino-3,8-dimethyl-3H-imidazo[4,5-f]quinoxaline-13C,15N2
2-Amino-3,8-DiMeIQx-13C,15N2
Stable Isotope Labeled MeIQx
[13C1,15N2]-2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline
Internal Standard for MeIQx
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-3,8-Dimethylimidazo[4,5-F]Quinoxaline-13C,15N2 is manufactured and analyzed under strict quality systems. Our products undergo rigorous quality testing, including isotopic purity and chemical purity verification via advanced techniques like NMR and HPLC-MS, to ensure compliance with research and analytical standards. A comprehensive Certificate of Analysis (COA) detailing batch-specific results for identity, purity, isotopic enrichment, and impurities is provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. Keep the container in a dry, cool, and well-ventilated place. For long-term storage, consider storing under inert atmosphere at lower temperatures (e.g., -20°C).

Specification

Item	Specification
Appearance	Off-white to light brown powder or crystalline solid
Identification (NMR)	Conforms to structure
Identification (HPLC-MS)	Conforms to reference
Purity (HPLC)	≥ 95% (Area %)
Isotopic Purity	≥ 98 atom % 13C; ≥ 98 atom % 15N
Chemical Purity	≥ 90% (by weight)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.