Description

Benzyl 4-(Bromophenyl)-Ether-D4 is a deuterated isotopologue of benzyl 4-bromophenyl ether, where four hydrogen atoms are replaced with deuterium. This high-purity labeled compound is critical for applications requiring precise analytical standards and metabolic pathway elucidation. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry industries for use as an internal standard in mass spectrometry and in the synthesis of deuterated active pharmaceutical ingredients (APIs).

Application

• Internal Standard for Quantitative Analysis: Serves as a stable, non-interfering internal standard in LC-MS and GC-MS for the accurate quantification of its non-deuterated counterpart and related metabolites.
• Pharmaceutical Research: Used in drug metabolism and pharmacokinetics (DMPK) studies to trace metabolic pathways and improve the detection sensitivity of parent drugs.
• Deuterated API Synthesis: Acts as a key synthetic intermediate or precursor in the development of deuterium-labeled drug candidates, which can offer improved metabolic stability.
• Analytical Reference Material: Provides a certified reference material for method development, validation, and quality control in analytical laboratories.
• Mechanistic Studies: Facilitates NMR-based structural and mechanistic studies in organic and medicinal chemistry due to the distinct spectroscopic properties of deuterium.

Basic Information

Product Name	Benzyl 4-(Bromophenyl)-Ether-D4
CAS No.	1185020-84-1
Molecular Formula	C13D4H9BrO
Molecular Weight	277.15 g/mol (deuterated form)
Synonyms	4-Bromophenyl Benzyl Ether-d4; Benzyl 4-Bromophenyl Ether-d4; 1-(Bromobenzene-4-oxy)-4-methylbenzene-d4; (4-Bromophenoxy)(phenyl)methane-d4; p-Bromophenyl Benzyl Ether-d4; Deuterated Benzyl 4-Bromophenyl Ether; [D4]-Benzyl 4-bromophenyl ether
EINECS	Contact for details

Quality Control

Our Benzyl 4-(Bromophenyl)-Ether-D4 is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and MS, to confirm chemical identity, isotopic purity (D-enrichment), and chemical purity. A detailed Certificate of Analysis (COA) specifying batch-specific results is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake. Handle and store in accordance with all applicable laboratory safety regulations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.