Description

1,3-Cyclohexanedione-1,2,3-13C3 is a stable isotope-labeled analog of 1,3-cyclohexanedione, where three carbon atoms are replaced with the carbon-13 isotope. This compound is essential for advanced analytical research, providing a critical internal standard for precise quantification and metabolic pathway tracing using mass spectrometry. It is primarily required by pharmaceutical R&D laboratories, agrochemical scientists, and academic institutions engaged in pharmacokinetic studies, environmental fate analysis, and the development of novel synthetic methodologies.

Application

• Internal Standard for Quantitative Mass Spectrometry (MS): Used as a reference compound in LC-MS and GC-MS analyses for accurate quantification of unlabeled 1,3-cyclohexanedione and its derivatives in complex biological or environmental matrices.
• Metabolic Pathway Tracing: Enables the study of biochemical pathways and degradation mechanisms in pharmaceutical and agrochemical research by tracking the incorporation of the 13C label.
• Isotope Dilution Analysis: Serves as a spike in isotope dilution mass spectrometry (IDMS) methods to achieve high-precision and high-accuracy measurements, crucial for regulatory and quality control laboratories.
• NMR Spectroscopy Studies: Facilitates structural elucidation and reaction mechanism studies by providing distinct 13C-NMR signals, reducing signal overlap.
• Synthesis of Labeled Complex Molecules: Acts as a key labeled building block for the synthesis of more complex 13C-labeled target molecules for research purposes.

Basic Information

Product Name	1,3-Cyclohexanedione-1,2,3-13C3
CAS No.	1184998-71-7
Molecular Formula	C313C3H8O2
Molecular Weight	~116.09 (based on 13C substitution)
Synonyms	1,3-Cyclohexanedione-13C3; [1,2,3-13C3]-1,3-Cyclohexanedione; 1,3-Cyclohexanedione (1,2,3-13C3); Cyclohexane-1,3-dione-1,2,3-13C3; Dimedone-13C3; 5,5-Dimethyl-1,3-cyclohexanedione-13C3 (related compound); Isotopically labeled 1,3-cyclohexanedione; 13C3-1,3-CHD
EINECS	Contact for details

Quality Control

Our 1,3-Cyclohexanedione-1,2,3-13C3 is manufactured under controlled conditions to ensure high isotopic and chemical purity, meeting the stringent requirements of analytical research. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (Atom % 13C), chemical purity by HPLC, and identity confirmation by spectroscopic methods. We adhere to ISO 9001 quality management principles, and our processes are designed to ensure batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (Atom % 13C)	≥ 99% on labeled positions
Chemical Purity (Titration)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.