Description

9-[[2-Benzyloxy-1-(Benzyloxymethyl)-Ethoxy]-Methyl]-6-Chloroguanine-D5 is a deuterated derivative of a nucleoside analogue precursor, offering a stable isotope-labeled standard for advanced research and development. This compound is critical for ensuring accuracy and reliability in quantitative analytical methods, particularly in pharmacokinetic and metabolic studies. It is primarily utilized by pharmaceutical researchers and analytical laboratories engaged in the development of antiviral and anticancer therapeutics.

Application

• As an internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for the quantification of related guanine analogues.
• For metabolic pathway tracing and drug metabolism studies in preclinical pharmaceutical research.
• In the synthesis and development of deuterium-labeled pharmaceutical agents to enhance metabolic stability.
• As a key reference material in quality control laboratories for ensuring batch-to-batch consistency of active pharmaceutical ingredients (APIs).
• For fundamental biochemical research investigating the mechanisms of nucleoside-based drugs.

Basic Information

Product Name	9-[[2-Benzyloxy-1-(Benzyloxymethyl)-Ethoxy]-Methyl]-6-Chloroguanine-D5
CAS No.	1184968-31-7
Molecular Formula	C22H20D5ClN5O3
Molecular Weight	Contact for details
Synonyms	6-Chloro-9-[[2-(benzyloxy)-1-[(benzyloxy)methyl]ethoxy]methyl]-9H-guanine-d5; Deuterated 6-Chloroguanine Benzyloxy Derivative; 6-Chloro-9-((2-(benzyloxy)-1-((benzyloxy)methyl)ethoxy)methyl)-9H-guanine-d5; 9-[[2-Benzyloxy-1-(Benzyloxymethyl)ethoxy]methyl]-6-chloro-9H-guanine-d5; 6-Chloroguanine-d5 benzyl protected precursor; [D5]-Labeled 6-Chloro-9-(2,3-bis(benzyloxy)propyl)guanine
EINECS	Contact for details

Quality Control

Our deuterated compounds are produced under strict quality systems to ensure isotopic purity and chemical integrity. Each batch is characterized by advanced spectroscopic methods, including NMR and Mass Spectrometry, to confirm the deuteration level and chemical structure. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and identification data is provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider conditions under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC-MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.