Description

Emd638683 CAS NO 1181770-72-8 is a high-purity, non-natural amino acid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of novel peptides and bioactive molecules, enabling the exploration of new therapeutic modalities. It is primarily utilized by pharmaceutical companies and contract research organizations (CROs) engaged in drug discovery, particularly for projects targeting metabolic disorders and oncology.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of investigational new drugs (INDs) and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used as a modified amino acid residue in solid-phase and solution-phase peptide synthesis to introduce specific functionalities.
• Bioconjugation: Employed in the development of antibody-drug conjugates (ADCs) and other targeted drug delivery systems.
• Medicinal Chemistry Research: Serves as a scaffold for constructing focused libraries to study structure-activity relationships (SAR).
• Biochemical Tool: Utilized in proteomics and enzymology studies as a substrate or inhibitor analog.
• Academic Research: A valuable reagent for universities and institutes conducting fundamental research in chemical biology and synthetic methodology.

Basic Information

Product Name	Emd638683
CAS No.	1181770-72-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	EMD 638683; (2S)-2-Amino-3-(4-fluorophenyl)propanoic acid tert-butyl ester; Fmoc-4-F-Phe-OH; 4-Fluoro-L-phenylalanine derivative; Boc-4-F-Phe-OH; N-Protected 4-fluorophenylalanine; Amino acid building block 1181770-72-8; Fluorinated phenylalanine analog
EINECS	Contact for details

Quality Control

Our Emd638683 is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep the container tightly sealed in a desiccator when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.