Description

6-Fluoroisoquinoline-1-Carboxylic Acid is a high-purity fluorinated isoquinoline derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in its role as a versatile intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and advanced materials. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorine atoms into heterocyclic scaffolds to modulate biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, especially in oncology, neurology, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides where the fluorinated isoquinoline core can enhance efficacy and environmental profile.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology & Proteomics: Employed in the design of molecular probes and tags for studying biological systems and protein interactions.
• Academic & Contract Research: A valuable reagent for methodological development in organic synthesis and fluorine chemistry within university and CRO laboratories.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	6-Fluoroisoquinoline-1-Carboxylic Acid
CAS No.	1179149-37-1
Molecular Formula	C10H6FNO2
Molecular Weight	191.16 g/mol
Synonyms	1-Isoquinolinecarboxylic acid, 6-fluoro-; 6-Fluoro-1-isoquinolinecarboxylic acid; 6-Fluoro-isoquinoline-1-carboxylic acid; 6-Fluoroisoquinoline-1-carboxylic acid; 1179149-37-1; 6-Fluoro-1-carboxyisoquinoline; 6-Fluoro-1-isoquinoline carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Fluoroisoquinoline-1-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.