Description

(5-Chloro-2-Methoxy-Phenyl)-Methanesulfonyl Chloride is a specialized sulfonyl chloride derivative, a key building block in advanced organic synthesis. This compound is valued for its dual reactive sites, enabling its use as a versatile electrophile for introducing the methanesulfonyl (mesyl) group or for further functionalization. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, intermediates, and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for sulfonamide-based drugs and other bioactive molecules.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the sulfonyl moiety is a key pharmacophore.
• Chemical Research & Development: Serves as a versatile electrophilic reagent in organic synthesis for C-S bond formation and as a protecting group precursor in multi-step synthetic routes.
• Material Science: Potential monomer or cross-linking agent in the development of specialized polymers and functional materials.
• Custom Synthesis & Contract Manufacturing: An essential building block for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	(5-Chloro-2-Methoxy-Phenyl)-Methanesulfonyl Chloride
CAS No.	1179047-05-2
Molecular Formula	C8H8Cl2O3S
Molecular Weight	255.12 g/mol
Synonyms	5-Chloro-2-methoxybenzenesulfonyl chloride; 1-Chloro-4-methoxy-2-(chloromethylsulfonyl)benzene; (5-Chloro-2-methoxyphenyl)methanesulfonyl chloride; 2-Methoxy-5-chlorophenyl methanesulfonyl chloride; Methanesulfonyl chloride, (5-chloro-2-methoxyphenyl)-; 5-Chloro-2-methoxybenzene-1-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our (5-Chloro-2-Methoxy-Phenyl)-Methanesulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as identity, assay, and impurity profiles. Our quality management system supports compliance with cGMP and ISO standards for research and industrial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its reactivity as a strong acid/organic solvent derivative, keep away from heat, sparks, open flames, and incompatible materials such as bases, amines, and oxidizing agents. Handle and store under an inert atmosphere if specified for optimal long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.