Description

(2-Bromo-4-Fluorophenyl)Methanesulfonyl Chloride is a high-purity, multi-functional chemical building block essential for advanced organic synthesis. Its core value lies in its dual functionality as a sulfonyl chloride and a halogenated aromatic, enabling precise molecular construction in complex chemical pathways. This compound is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of sulfonamide-based drug candidates, including kinase inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of new herbicides and fungicides, leveraging the bromo and fluoro substituents for bioactivity.
• Material Science Research: Serves as a monomer or cross-linking agent in the creation of specialty polymers with unique electronic or surface properties.
• Chemical Biology Probes: Employed in the design of activity-based probes (ABPs) for studying enzyme function and mechanism.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses producing bespoke compounds for client R&D programs.

Basic Information

Product Name	(2-Bromo-4-Fluorophenyl)Methanesulfonyl Chloride
CAS No.	1178315-16-6
Molecular Formula	C7H5BrClFO2S
Molecular Weight	287.53 g/mol
Synonyms	2-Bromo-4-fluorobenzene-1-sulfonyl chloride; 1-Bromo-2-fluoro-4-(chlorosulfonyl)benzene; (2-Bromo-4-fluorobenzene)sulfonyl chloride; 4-Fluoro-2-bromobenzenesulfonyl chloride; 2-Bromo-4-fluorophenylsulfonyl chloride; α-Bromo-α'-fluoro-m-benzenedisulfonyl chloride (related); Benzenesulfonyl chloride, 2-bromo-4-fluoro-
EINECS	Contact for details

Quality Control

Every batch of (2-Bromo-4-Fluorophenyl)Methanesulfonyl Chloride is produced and tested under a strict quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.