Description

Mmp-9 Inhibitor I CAS NO 1177749-58-4 is a potent and selective small molecule inhibitor of Matrix Metalloproteinase-9 (MMP-9), a key enzyme implicated in extracellular matrix remodeling. This compound is a critical research tool for investigating the role of MMP-9 in various pathological processes, including cancer metastasis, inflammatory diseases, and tissue degradation. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on developing novel therapeutic strategies.

Application

• Biomedical Research: Used as a selective pharmacological probe to study the specific functions and signaling pathways of MMP-9 in in vitro and in vivo disease models.
• Oncology Research: Investigation of tumor invasion, angiogenesis, and metastasis mechanisms, aiding in the discovery of new anti-cancer drug targets.
• Inflammation & Immunology Studies: Research into conditions like rheumatoid arthritis, atherosclerosis, and chronic obstructive pulmonary disease (COPD) where MMP-9 activity is dysregulated.
• Neurological Disease Research: Exploration of its role in neuroinflammation, blood-brain barrier disruption, and diseases such as multiple sclerosis and stroke.
• Drug Discovery & Development: Serves as a lead compound or reference standard for screening and optimizing new MMP-9 inhibitors in preclinical development pipelines.
• Biochemical Assay Development: Used as a control inhibitor in enzymatic activity assays (e.g., fluorogenic or colorimetric assays) to validate assay performance and specificity.

Basic Information

Product Name	Mmp-9 Inhibitor I
CAS No.	1177749-58-4
Molecular Formula	C₂₀H₂₀N₄O₃
Molecular Weight	364.40 g/mol
Synonyms	(S)-N-Hydroxy-1-(2-Methyl-4'-(methylsulfonyl)biphenyl-4-yl)-5-oxopyrrolidine-3-carboxamide; (S)-N-Hydroxy-5-oxo-1-[4'-(methylsulfonyl)-2-methylbiphenyl-4-yl]pyrrolidine-3-carboxamide; MMP-9 Inhibitor I; CAS 1177749-58-4; MMP9 Inhibitor; MMP-9 Inhibitor
EINECS	Contact for details

Quality Control

Our Mmp-9 Inhibitor I is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccated conditions. This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and potency. Allow the vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (Mass Spectrometry)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Solubility	Soluble in DMSO, Methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.