Description

Caspase-13 Inhibitor I is a potent and selective small-molecule inhibitor designed to target the caspase-13 enzyme, a key mediator in specific inflammatory and apoptotic pathways. This compound is essential for researchers and developers in the life sciences sector, providing a critical tool for elucidating biological mechanisms and validating novel therapeutic targets. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on inflammation, immunology, and programmed cell death studies.

Application

• Biochemical Research: A vital tool for studying the specific role and inhibition kinetics of caspase-13 in in vitro enzyme assays.
• Cell Biology Studies: Used to investigate caspase-13-mediated apoptotic and inflammatory signaling pathways within cell culture models.
• Drug Discovery & Validation: Serves as a reference compound and pharmacological probe for screening and validating new anti-inflammatory or anti-apoptotic drug candidates.
• Target Identification: Facilitates functional genomics and proteomics research aimed at understanding caspase-13 interactions and downstream effects.
• Preclinical Development: Employed in proof-of-concept studies to assess the therapeutic potential of caspase-13 inhibition in relevant disease models.

Basic Information

Product Name	Caspase-13 Inhibitor I
CAS No.	1177489-18-7
Molecular Formula	C21H19N3O4S
Molecular Weight	409.46 g/mol
Synonyms	Z-Asp-2,6-Dichlorobenzoyloxymethylketone; Z-Asp-CH2-DCB; Caspase-13 Inhibitor Z-Asp-CH2-DCB; (Benzyloxycarbonyl)-Aspartic acid 1-[(2,6-dichlorobenzoyl)oxy]methyl ketone; Z-Asp(OMe)-DCB; Caspase Inhibitor XIII; Z-Asp-2,6-DCB; Caspase-13 Selective Inhibitor
EINECS	Contact for details

Quality Control

Our Caspase-13 Inhibitor I is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC purity analysis, NMR structural confirmation, and mass spectrometry. A detailed Certificate of Analysis (COA) documenting identity, purity, and quality is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with reference structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.