Description

1-Isopropyl-1H-Pyrazole-4-Sulfonyl Chloride is a versatile and reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its role as a key intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This high-purity intermediate is essential for research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality raw materials for their synthetic routes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting various enzyme families where the sulfonamide moiety is pharmacologically active.
• Agrochemical Synthesis: Used in the production of modern herbicides, fungicides, and insecticides, where the pyrazole-sulfonyl chloride structure imparts specific biological activity.
• Functional Material Development: Serves as a building block for creating specialized polymers, ligands, or dyes with tailored properties.
• Chemical Biology & Proteomics: Employed as a reactive handle for labeling or modifying biomolecules in research applications.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing client-specific compounds.

Basic Information

Product Name	1-Isopropyl-1H-Pyrazole-4-Sulfonyl Chloride
CAS No.	1177336-51-4
Molecular Formula	C6H9ClN2O2S
Molecular Weight	208.67 g/mol
Synonyms	1-Isopropyl-1H-pyrazole-4-sulfonyl chloride; 1H-Pyrazole-4-sulfonyl chloride, 1-(1-methylethyl)-; 1-(Propan-2-yl)-1H-pyrazole-4-sulfonyl chloride; 1-Isopropylpyrazole-4-sulfonyl chloride; 4-(Chlorosulfonyl)-1-isopropyl-1H-pyrazole; Isopropylpyrazole sulfonyl chloride; Pyrazole-4-sulfonyl chloride, 1-isopropyl derivative
EINECS	Contact for details

Quality Control

Our 1-Isopropyl-1H-Pyrazole-4-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent quality suitable for demanding synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.